BDBM543569 US11279703, TABLE 6.158::US11279703, TABLE 6.169::US11643396, Example SG4-032

SMILES CN1CCN(CC1)c1ccc(Nc2ncc(C)c(Nc3ccc4CCN(c4c3)S(=O)(=O)C(C)(C)C)n2)cc1F

InChI Key InChIKey=VAVUXBJDHMBDDT-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 543569   

TargetBromodomain-containing protein 2 [91-163](Homo sapiens (Human))
Aptose Biosciences

US Patent
LigandPNGBDBM543569(US11279703, TABLE 6.158 | US11279703, TABLE 6.169 ...)
Affinity DataIC50:  254nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent